Urokinase mutant with better fibrin-specificity.

Article

Urokinase mutant with better fibrin-specificity.

Science in China. Series C, Life sciences - 1 Oct 1996

Ma Z, Yu R, Hua Z, Zhu D

Abstract excerpt

A 150-156 amino acids-deleted single-chain urokinase-type plasminogen activator (dscu-PA) and its recombinant wild-type counterpart (rscu-PA) were both expressed in Escherichia coli. After denaturation and renaturation in vitro, the expressed products were both purified to a single silver-stained...

Topics

Amino Acid Sequence
Escherichia coli
Fibrin
Molecular Sequence Data
Mutation
Plasminogen Activators
Protein Engineering
Recombinant Proteins
Urokinase-Type Plasminogen Activator

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