TP53 and hepatocellular carcinoma.

Article

TP53 and hepatocellular carcinoma.

Pathologie-biologie - 1 Dec 1997

Puisieux A, Ozturk M

Abstract excerpt

TP53 gene mutations occur in 30 to 55% hepatocellular carcinomas. Both the frequency and the type of p53 mutations in HCC vary according to geographical location of tumors. A specific mutation at codon 249 (AGG-->AGT) was found at high frequency in tumors from high aflatoxin-areas. TP53 mutations...

Topics

Carcinoma, Hepatocellular
Genes, p53
Humans
Liver
Liver Neoplasms
Mutation
Reference Values

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