Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Spatio-temporal control of oncogenesis].

Pathologie-biologie - 1 Feb 1998

Giovannini M

Abstract excerpt

Experimental carcinogenesis has, until recently, relied on the use of animal models in which the tumorigenic process is distantly related to that observed in humans. More recently the use of transgenic mice has open new opportunities but has also revealed two limitations: firstly, some of the most prominent tumors observed in genetically predisposed humans are not observed in the corresponding mice; secondly, in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Models, Animal
Share to Genes, Tumor Suppressor
Share to Mice

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Knockout

Share to Mice, Transgenic

Share to Mutation

Share to Oncogenes

Share to Time Factors

Source

Identifiers

PMID: 9769926

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Spatio-temporal control of oncogenesis].PMID 9769926Read ↗

[Mouse models of K-ras-initiated oncogenesis].Semantic proximity Read ↗

A mouse model to study inducible oncogene cooperation in vivoSemantic proximity Read ↗

Site- and time-specific gene targeting in the mouse.Semantic proximity Read ↗

Temporal dissection of K-ras(G12D) mutant in vitro and in vivo using a regulatable K-ras(G12D) mouse allele.Semantic proximity Read ↗

Cre-mediated somatic site-specific recombination in miceSemantic proximity Read ↗

Activated N-ras oncogene and N-ras proto-oncogene act through the same pathway for in vivo tumorigenesis.Semantic proximity Read ↗

Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis.Semantic proximity Read ↗

Germ-line expression of an oncogenic erbB2 allele confers resistance to erbB2-induced mammary tumorigenesis.Semantic proximity Read ↗

High levels of phosphorylated c-Jun, Fra-1, Fra-2 and ATF-2 proteins correlate with malignant phenotypes in the multistage mouse skin carcinogenesis model.Semantic proximity Read ↗

Reversible tumorigenesis in mice by conditional expression of the HER2/c-erbB2 receptor tyrosine kinase.Semantic proximity Read ↗

Induction of a variety of tumors by c-erbB2 and clonal nature of lymphomas even with the mutated gene (Val659----Glu659).Semantic proximity Read ↗

Ets2-dependent microenvironmental support of mouse mammary tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.