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Article

Ets2-dependent microenvironmental support of mouse mammary tumors.

Oncogene - 20 Oct 2005

Tynan John A, Wen Fang, Muller William J, Oshima Robert G

Abstract excerpt

Decreasing the amount of active mouse Ets2 transcription factor by half in mice or use of a MAP kinase insensitive hypomorphic targeted Ets2 allele restricts the appearance of transgenic mammary tumors caused by either Polyoma middle T antigen (PyMT) or activated Neu/ErbB2. In addition, the early growth of transplanted mammary tumors is limited by restricted Ets2 activity of the host. Here we have tested...

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PMID: 16007139
DOI: 10.1038/sj.onc.1208856

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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