Article
Assignment of the L30-mRNA complex using selective isotopic labeling and RNA mutants.
Nucleic acids research - 15 Oct 1999
Mao H, Williamson J R
Abstract excerpt
The helix-loop-helix structure formed in the pre-mRNA and the mRNA of L30, a ribosomal protein from the yeast Saccharomyces cerevisiae, serves as an auto-regulatory binding site for the protein to suppress the L30 synthesis upon overproduction. Using a 33-nucleotide model RNA, the structures of the L30 binding site RNA in the presence and absence of the protein were investigated using nuclear magnetic resonance...
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