Reovirus reverse genetics: Incorporation of the CAT gene into the reovirus genome

Abstract excerpt

We have modified the infectious reovirus RNA system so as to generate a reovirus reverse genetics system. The system consists of (i) the plus strands of nine wild-type reovirus genome segments; (ii) transcripts of the genetically modified cDNA form of the tenth genome segment; and (iii) a cell line transformed so as to express the protein normally encoded by the tenth genome segment. In the work described here,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Vector-Borne Animal Diseases
• Share to Viral gastroenteritis research and epidemiology
• Share to Virus-based gene therapy research