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Article

Virion disassembly is required for apoptosis induced by reovirus.

Journal of virology - 1 Feb 2002

Connolly Jodi L, Dermody Terence S

Abstract excerpt

Reovirus infection leads to apoptosis in cultured cells and in vivo. Binding of viral attachment protein final sigma 1 to both sialic acid and junction adhesion molecule is required for induction of apoptosis. However, it is not known whether viral engagement of receptors is sufficient to elicit this cellular response. To determine whether steps in reovirus replication subsequent to viral attachment are required...

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Identifiers

PMID: 11799158
DOI: 10.1128/jvi.76.4.1632-1641.2002
PMCID: PMC135877

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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