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Article

A post-entry step in the mammalian orthoreovirus replication cycle is a determinant of cell tropism.

The Journal of biological chemistry - 31 Dec 2010

Ooms Laura S, Kobayashi Takeshi, Dermody Terence S, Chappell James D

Abstract excerpt

Mammalian reoviruses replicate in a broad range of hosts, cells, and tissues. These viruses display strain-dependent variation in tropism for different types of cells in vivo and ex vivo. Early steps in the reovirus life cycle, attachment, entry, and disassembly, have been identified as pivotal p...

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Identifiers

PMID: 20978124
DOI: 10.1074/jbc.M110.176255
PMCID: PMC3009888

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20978124-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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