Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-Mobility Group 1/2 Proteins Are Essential for Initiating Rolling-Circle-Type DNA Replication at a Parvovirus Hairpin Origin

1 Nov 1998

Abstract excerpt

Rolling-circle replication is initiated by a replicon-encoded endonuclease which introduces a single-strand nick into specific origin sequences, becoming covalently attached to the 5' end of the DNA at the nick and providing a 3' hydroxyl to prime unidirectional, leading-strand synthesis. Parvoviruses, such as minute virus of mice (MVM), have adapted this mechanism to amplify their linear single-stranded genomes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Virus Infections Studies
Share to Parvovirus B19 Infection Studies
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9765384
DOI: 10.1128/jvi.72.11.8477-8484.1998

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-Mobility Group 1/2 Proteins Are Essential for Initiating Rolling-Circle-Type DNA Replication at a Parvovirus Hairpin OriginPMID 9765384Read ↗

The human parvovirus B19 non-structural protein 1 N-terminal domain specifically binds to the origin of replication in the viral DNASemantic proximity Read ↗

LINE-1 ribonucleoprotein complexes bind DNA to enable nuclear entry during mitosisSemantic proximity Read ↗

Analysis of <i>cis</i> and <i>trans</i> Requirements for DNA Replication at the Right-End Hairpin of the Human Bocavirus 1 GenomeSemantic proximity Read ↗

Structure of the NS1 Protein N-Terminal Origin Recognition/Nickase Domain from the Emerging Human BocavirusSemantic proximity Read ↗

Sequence motifs in the replicator protein of parvovirus MVM essential for nicking and covalent attachment to the viral origin: identification of the linking tyrosine.Semantic proximity Read ↗

G-quadruplex as an essential structural element in cytomegalovirus replication originSemantic proximity Read ↗

Structures of vertebrate R2 retrotransposon complexes during target-primed reverse transcription and after second strand nickingSemantic proximity Read ↗

Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integritySemantic proximity Read ↗

Replication of an Autonomous Human Parvovirus in Non-dividing Human Airway Epithelium Is Facilitated through the DNA Damage and Repair PathwaysSemantic proximity Read ↗

Asymmetric replication in vitro from a human sequence element is dependent on adeno-associated virus Rep proteinSemantic proximity Read ↗

Identification of a Functionally Relevant Adeno-Associated Virus Rep68 Oligomeric Interface.Semantic proximity Read ↗

Segregation of a single outboard left-end origin is essential for the viability of parvovirus minute virus of mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.