Article
Sequence motifs in the replicator protein of parvovirus MVM essential for nicking and covalent attachment to the viral origin: identification of the linking tyrosine.
Virology - 10 May 1995
Nüesch J P, Cotmore S F, Tattersall P
Abstract excerpt
Parvoviral DNA replication has many features in common with prokaryotic rolling circle replication (RCR), including the pivotal role of an initiator protein which introduces a site-specific, single strand nick into a duplex origin sequence. In this process, the protein becomes covalently attached...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- DNA Helicases
- DNA Primers
- DNA Replication
- DNA, Viral
- HeLa Cells
- Humans
- Mice
- Minute Virus of Mice
- Molecular Sequence Data
- Mutation
- Plasmids
- Polymerase Chain Reaction
- Replication Origin
- Vaccinia virus