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Article

Identification of a Functionally Relevant Adeno-Associated Virus Rep68 Oligomeric Interface.

Journal of virology - 1 Aug 2016

Bardelli Martino, Zárate-Pérez Francisco, Agúndez Leticia, Linden R Michael, Escalante Carlos R, Henckaerts Els

Abstract excerpt

UNLABELLED: The life cycle of the human parvovirus adeno-associated virus (AAV) is orchestrated by four Rep proteins. The large Rep proteins, Rep78 and Rep68, are remarkably multifunctional and display a range of biochemical activities, including DNA binding, nicking, and unwinding. Functionally, Rep78 and Rep68 are involved in transcriptional regulation, DNA replication, and genomic integration. Structurally,...

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Source

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Identifiers

PMID: 27170758
DOI: 10.1128/JVI.00356-16
PMCID: PMC4944284

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification of a Functionally Relevant Adeno-Associated Virus Rep68 Oligomeric Interface.PMID 27170758Read ↗

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