Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Induction of Rb-associated Protein (RbAp46) by Wilms' Tumor Suppressor WT1 Mediates Growth Inhibition

1 Oct 1998

Abstract excerpt

The Wilms' tumor suppressor gene, wt1, encodes a zinc-finger transcription factor, WT1, that plays an important role in controlling urogenital development. Previously, WT1 has been shown to inhibit cell growth and to repress transcription initiated from the promoters of a number of growth-promoting genes. However, few physiological target genes that are transcriptionally activated by WT1 have been established....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ethics and Legal Issues in Pediatric Healthcare
Share to Renal and related cancers

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9765217
DOI: 10.1074/jbc.273.42.27047

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Induction of Rb-associated Protein (RbAp46) by Wilms' Tumor Suppressor WT1 Mediates Growth InhibitionPMID 9765217Read ↗

WT1 targetsGas1to maintain nephron progenitor cells by modulating FGF signalsSemantic proximity Read ↗

WT1-Mediated Gene Regulation in Early Urogenital Ridge DevelopmentSemantic proximity Read ↗

The functions of Wt1 in mouse gonad development and somatic cells differentiationSemantic proximity Read ↗

Wilms' tumor protein Wt1 is an activator of the anti-Müllerian hormone receptor gene Amhr2.Semantic proximity Read ↗

Classification of a frameshift/extended and a stop mutation in WT1 as gain-of-function mutations that activate cell cycle genes and promote Wilms tumour cell proliferation.Semantic proximity Read ↗

Control of epigenetic states by WT1 via regulation of de novo DNA methyltransferase 3ASemantic proximity Read ↗

Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1.Semantic proximity Read ↗

A new role for wilms tumor protein 1: differential activities of + KTS and -KTS variants to regulate LHβ transcription.Semantic proximity Read ↗

Identification of WTAP, a novel Wilms' tumour 1-associating proteinSemantic proximity Read ↗

Ubiquitin specific protease 18 (Usp18) is a WT1 transcriptional target.Semantic proximity Read ↗

Expression of inhibin-alpha is regulated synergistically by Wilms' tumor gene 1 (Wt1) and steroidogenic factor-1 (Sf1) in sertoli cells.Semantic proximity Read ↗

WT1: a novel tumor suppressor gene inactivated in Wilms' tumor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.