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Article

Wilms' tumor protein Wt1 is an activator of the anti-Müllerian hormone receptor gene Amhr2.

Molecular and cellular biology - 1 Jun 2007

Klattig Jürgen, Sierig Ralph, Kruspe Dagmar, Besenbeck Birgit, Englert Christoph

Abstract excerpt

The Wilms' tumor protein Wt1 plays an essential role in mammalian urogenital development. WT1 mutations in humans lead to a variety of disorders, including Wilms' tumor, a pediatric kidney cancer, as well as Frasier and Denys-Drash syndromes. Phenotypic anomalies in Denys-Drash syndrome include pseudohermaphroditism and sex reversal in extreme cases. We have used cDNA microarray analyses on Wt1 knockout mice to...

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Share to Genes, Wilms Tumor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Peptide

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Source

Open in PubMed Open full text

Identifiers

PMID: 17420277
DOI: 10.1128/MCB.01780-06
PMCID: PMC1900060

Genes

AMHR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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