Article
Separable effects of human Kvbeta1.2 N- and C-termini on inactivation and expression of human Kv1.4.
The Journal of physiology - 15 Oct 1998
Accili E A, Kuryshev Y A, Wible B A, Brown A M
Abstract excerpt
1. The Kvbeta subunits of voltage-gated K+ channels alter the functional expression and gating of non- or slowly inactivating Kvalpha1 subunits via two separate domains. To determine how Kvbeta subunits modulate a rapidly inactivating Kvalpha1 subunit, we did two-microelectrode voltage clamp experiments on human Kv1.4 voltage-gated K+ channels expressed heterologously in Xenopus oocytes. In addition we tested a...
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