Article
Gathering STYX: phosphatase-like form predicts functions for unique protein-interaction domains.
Trends in biochemical sciences - 1 Aug 1998
Wishart M J, Dixon J E
Abstract excerpt
The effects of tyrosine phosphorylation are manifested and regulated through protein domains that bind to specific phosphotyrosine motifs. STYX is a unique modular domain found within proteins implicated in mediating the effects of tyrosine phosphorylation in vivo. Individual STYX domains are not catalytically active; however, they resemble protein tyrosine phosphatase (PTP) domains and, like PTPs, contain core...
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