Article
Loss of human leukocyte antigen expression on colorectal tumor cell lines: implications for anti-tumor immunity and immunotherapy.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy - 1 Oct 1993
Browning M J, Krausa P, Rowan A, Hill A B, Bicknell D C, Bodmer J G, Bodmer W F
Abstract excerpt
A system devised for tissue typing the human leukocyte antigen-A (HLA-A) locus from genomic DNA by the polymerase chain reaction (PCR) has been used to investigate abnormalities of HLA expression in a panel of 30 cell lines derived from colorectal adenocarcinomas, by comparison of the HLA-A locus genotype with surface expression of HLA. Eleven cell lines gave single HLA-A locus specificity on PCR typing,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
