Growth factor receptors as targets for therapy in pediatric brain tumors.

Abstract excerpt

Growth factor receptors (GFRs) have been described as overexpressed in several types of brain tumors. Overexpression of these transmembrane proteins is considered to be an important part of tumorigenesis. Genetic as well as epigenetic modulation of the receptors have to be considered when trying to understand the role of GFRs in tumors or as targets for tumor therapy. GFR function can be modulated by membrane...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Brain
• Share to Brain Neoplasms
• Share to Child