Growth factor receptors as targets for therapy in pediatric brain tumors.

doi:10.1159/000028677

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Article

Growth factor receptors as targets for therapy in pediatric brain tumors.

Pediatric neurosurgery - 1 Jul 1998

Meuillet E J, Bremer E G

Abstract excerpt

Growth factor receptors (GFRs) have been described as overexpressed in several types of brain tumors. Overexpression of these transmembrane proteins is considered to be an important part of tumorigenesis. Genetic as well as epigenetic modulation of the receptors have to be considered when trying...

Topics

Animals
Brain
Brain Neoplasms
Child
Gangliosides
Gene Expression
Glioma
Humans
Mutation
Rats
Receptors, Growth Factor
Treatment Outcome

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