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Article

Srb/mediator proteins interact functionally and physically with transcriptional repressor Sfl1.

The EMBO journal - 1 Oct 1998

Song W, Carlson M

Abstract excerpt

Srb/mediator proteins that are associated with RNA polymerase II holoenzyme have been implicated in transcriptional repression in Saccharomyces cerevisiae. We show here that the defect in repression of SUC2 caused by mutation of SRB8, SRB9, SRB11, SIN4 or ROX3 is suppressed by increased dosage of the SFL1 gene, and the genetic behavior of the sfl1Delta mutation provides further evidence for a functional...

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Identifiers

PMID: 9755175
DOI: 10.1093/emboj/17.19.5757
PMCID: PMC1170903

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Srb/mediator proteins interact functionally and physically with transcriptional repressor Sfl1.PMID 9755175Read ↗

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Sfl1 functions via the co-repressor Ssn6-Tup1 and the cAMP-dependent protein kinase Tpk2.Semantic proximity Read ↗

An activator binding module of yeast RNA polymerase II holoenzyme.Semantic proximity Read ↗

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