Article
Srb/mediator proteins interact functionally and physically with transcriptional repressor Sfl1.
The EMBO journal - 1 Oct 1998
Song W, Carlson M
Abstract excerpt
Srb/mediator proteins that are associated with RNA polymerase II holoenzyme have been implicated in transcriptional repression in Saccharomyces cerevisiae. We show here that the defect in repression of SUC2 caused by mutation of SRB8, SRB9, SRB11, SIN4 or ROX3 is suppressed by increased dosage of...
Topics
- Bacterial Proteins
- Binding Sites
- Cyclin-Dependent Kinases
- Cyclins
- DNA-Binding Proteins
- Fungal Proteins
- Gene Dosage
- Gene Expression Regulation, Fungal
- Genes, Reporter
- Glycoside Hydrolases
- Mediator Complex
- Models, Genetic
- Mutation
- Precipitin Tests
- Protein Binding
- RNA Polymerase II
- Recombinant Fusion Proteins
- Repressor Proteins