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Article

SSN genes that affect transcriptional repression in Saccharomyces cerevisiae encode SIN4, ROX3, and SRB proteins associated with RNA polymerase II.

Molecular and cellular biology - 1 Jan 1996

Song W, Treich I, Qian N, Kuchin S, Carlson M

Abstract excerpt

The RNA polymerase II of Saccharomyces cerevisiae exists in holoenzyme forms containing a complex, known as the mediator, associated with the carboxyl-terminal domain. The mediator includes several SRB proteins and is required for transcriptional activation. Previous work showed that a cyclin-dependent kinase-cyclin pair encoded by SSN3 and SSN8, two members of the SSN suppressor family, are identical to two SRB...

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Identifiers

PMID: 8524287
DOI: 10.1128/MCB.16.1.115
PMCID: PMC230984

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