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Article

Members of the SAGA and Mediator complexes are partners of the transcription elongation factor TFIIS.

The EMBO journal - 27 Oct 2004

Wery Maxime, Shematorova Elena, Van Driessche Benoît, Vandenhaute Jean, Thuriaux Pierre, Van Mullem Vincent

Abstract excerpt

TFIIS, an elongation factor encoded by DST1 in Saccharomyces cerevisiae, stimulates transcript cleavage in arrested RNA polymerase II. Two components of the RNA polymerase II machinery, Med13 (Srb9) and Spt8, were isolated as two-hybrid partners of the conserved TFIIS N-terminal domain. They belong to the Cdk8 module of the Mediator and to a subform of the SAGA co-activator, respectively. Co-immunoprecipitation...

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Identifiers

PMID: 15359273
DOI: 10.1038/sj.emboj.7600326
PMCID: PMC524382

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Members of the SAGA and Mediator complexes are partners of the transcription elongation factor TFIIS.PMID 15359273Read ↗

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