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Article

Incidence and clinical significance of hepatitis B virus precore gene translation initiation mutations in e antigen‐negative patients

1 Jul 1998

Abstract excerpt

Hepatitis Be antigen (HBeAg)-negative chronic hepatitis B (CHB) is associated with hepatitis B virus (HBV) variants harbouring changes in the precore region. Most commonly, a G to A point mutation at nucleotide 1896 (m1896) creates a novel translation stop codon that prevents HBeAg production. In the Mediterranean region the m1896 mutation prevails in greater than 98% of HBeAg-negative CHB patients. In this study...

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Identifiers

PMID: 9751010
DOI: 10.1046/j.1365-2893.1998.00109.x

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Incidence and clinical significance of hepatitis B virus precore gene translation initiation mutations in e antigen‐negative patientsPMID 9751010Read ↗

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