Article
Association of core promoter/precore mutations and viral load in e antigen-negative chronic hepatitis B patients.
Journal of viral hepatitis - 1 May 2006
Huang Y-H, Wu J-C, Chang T-T, Sheen I-J, Huo T-I, Lee P-C, Su C-W, Lee S-D
Abstract excerpt
Apart from core promoter A1762T/G1764A and precore G1896A mutations, other hepatitis B virus (HBV) mutants are detected in hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB). The aim of this study was to determine the effects of those mutants on clinical manifestation and viral loads of genotypes B and C HBV. Seventy-nine HBeAg-negative CHB patients with hepatitis flare were enrolled in this study...
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