Article
Genetic analysis of adenovirus E1A: induction of genetic instability and altered cell morphologic and growth characteristics are segregatable functions.
Mutation research - 12 Oct 1998
Drews R, Kolker M, Moran C, Sachar D, Chan V, Schnipper L
Abstract excerpt
Single multifunctional oncoproteins contribute to genomic instability development, but relationships between one or more oncoprotein-associated activities and genetic changes accompanying tumor cell progression are uncertain. Using NIH 3T3 derivative EN/NIH 2-20 containing transcriptionally silen...
Topics
- 3T3 Cells
- Adenoviridae
- Adenovirus E1A Proteins
- Animals
- Anti-Bacterial Agents
- Cell Division
- Cell Size
- Gene Expression
- Gene Rearrangement
- Genetic Complementation Test
- Gentamicins
- Kanamycin Kinase