Tumor suppression activity of adenovirus E1a protein: anoikis and the epithelial phenotype.

doi:10.1016/s0065-230x(01)80011-7

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Tumor suppression activity of adenovirus E1a protein: anoikis and the epithelial phenotype.

Advances in cancer research - 1 Jan 2001

Frisch S M

Abstract excerpt

Adenovirus E1a proteins reverse-transform diverse human tumor cells in culture. This has stimulated interest in the arenas of clinical and basic cancer research. Clinically, cancer gene therapy trials on E1a are in progress, and drug discovery strategies based on E1a are being considered. Biologically, the effect of E1a is unique in that it overrides most or all oncogenic signaling pathways to yield...

Topics

Adenovirus E1A Proteins
Anoikis
Epithelium
Genes, Tumor Suppressor
Neoplasms
Phenotype
Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 11034539
DOI: 10.1016/s0065-230x(01)80011-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics