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Article

Tumor suppression activity of adenovirus E1a protein: anoikis and the epithelial phenotype.

Advances in cancer research - 1 Jan 2001

Frisch S M

Abstract excerpt

Adenovirus E1a proteins reverse-transform diverse human tumor cells in culture. This has stimulated interest in the arenas of clinical and basic cancer research. Clinically, cancer gene therapy trials on E1a are in progress, and drug discovery strategies based on E1a are being considered. Biologically, the effect of E1a is unique in that it overrides most or all oncogenic signaling pathways to yield...

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PMID: 11034539
DOI: 10.1016/s0065-230x(01)80011-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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