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Article

Relevance of RET proto-oncogene mutations in sporadic medullary thyroid carcinoma.

The Journal of clinical endocrinology and metabolism - 1 Oct 1996

Wohllk N, Cote G J, Bugalho M M, Ordonez N, Evans D B, Goepfert H, Khorana S, Schultz P, Richards C S, Gagel R F

Abstract excerpt

Analysis of peripheral blood or tumor DNA samples from 101 patients with apparent sporadic medullary thyroid carcinoma (MTC) was performed to assess the frequency of RET proto-oncogene mutations in this patient population. Peripheral blood and/or tumor DNA was amplified by polymerase chain reaction. DNA sequence or restriction enzyme analysis was performed to detect mutations of RET proto-oncogene codons 609,...

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Source

Identifiers

PMID: 8855832
DOI: 10.1210/jcem.81.10.8855832

Genes

RET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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