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Article

Gastrointestinal signals in supplemented media reveal a role in adherence for the Shigella flexneri sap autotransporter gene.

Gut microbes - 1 Jan 2000

León Yrvin, Honigsberg Raphael, Rasko David A, Faherty Christina S

Abstract excerpt

Shigella flexneri causes severe diarrheal disease worldwide. While many aspects of pathogenesis have been elucidated, significant knowledge gaps remain regarding the role of putative chromosomally-encoded virulence genes. The uncharacterized sap gene encoded on the chromosome has significant nucleotide sequence identity to the fluffy (flu) antigen 43 autotransporter gene in pathogenic Escherichia coli. Here, we...

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Identifiers

PMID: 38549437
DOI: 10.1080/19490976.2024.2331985
PMCID: PMC10984119

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