Article
Analysis of isoprenoid biosynthesis in peroxisomal-deficient Pex2 CHO cell lines.
Journal of lipid research - 1 Sept 1998
Aboushadi N, Krisans S K
Abstract excerpt
ZR-78 and ZR-82 cells are two peroxisomal-deficient Chinese hamster ovary (CHO) cell mutants. These cells lack normal peroxisomes and show reduced levels of plasmalogen synthesis and other peroxisomal functions attributed to the deficiency of peroxisomal matrix enzymes. As we have recently identified two HMG-CoA reductase proteins in CHO cells, a 97 kDa reductase localized in the ER and a 90 kDa reductase protein...
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