Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Peroxisome biogenesis and molecular defects in peroxisome assembly disorders.

Cell biochemistry and biophysics - 1 Jan 2000

Fujiki Y, Okumoto K, Otera H, Tamura S

Abstract excerpt

Peroxisome assembly in mammals requires more than 14 genes. So far, we have isolated seven complementation groups (CGs) of peroxisome biogenesis-defective Chinese hamster ovary (CHO) cell mutants, Z65, Z24/ZP107, ZP92, ZP105/ZP139, ZP109, ZP110, ZP114. Two peroxin cDNAs, PEX2 and PEX6, were first cloned by genetic phenotype-complementation assay using Z65 and ZP92, respectively, and were shown to be responsible...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Peroxisomal Disorders
Share to Gene Expression Regulation
Share to Membrane Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Peroxisomes

Source

Identifiers

PMID: 11330042
DOI: 10.1385/cbb:32:1-3:155

Genes

PEX1
PEX12
PEX2
PEX5
PEX6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Peroxisome biogenesis and molecular defects in peroxisome assembly disorders.PMID 11330042Read ↗

Newly identified Chinese hamster ovary cell mutants defective in peroxisome assembly represent complementation group A of human peroxisome biogenesis disorders and one novel group in mammals.Semantic proximity Read ↗

Mutations in PEX10 is the cause of Zellweger peroxisome deficiency syndrome of complementation group B.Semantic proximity Read ↗

Lessons from peroxisome-deficient Chinese hamster ovary (CHO) cell mutants.Semantic proximity Read ↗

Peroxisome Biogenesis Disorders.Semantic proximity Read ↗

Newly identified Chinese hamster ovary cell mutants defective in peroxisome biogenesis represent two novel complementation groups in mammals.Semantic proximity Read ↗

Mutations in the peroxin Pex26p responsible for peroxisome biogenesis disorders of complementation group 8 impair its stability, peroxisomal localization, and interaction with the Pex1p x Pex6p complex.Semantic proximity Read ↗

Isolation of a new peroxisome-deficient CHO cell mutant defective in peroxisome targeting signal-1 receptor.Semantic proximity Read ↗

Molecular basis of peroxisomal biogenesis disorders caused by defects in peroxisomal matrix protein import.Semantic proximity Read ↗

PEX12, the pathogenic gene of group III Zellweger syndrome: cDNA cloning by functional complementation on a CHO cell mutant, patient analysis, and characterization of PEX12p.Semantic proximity Read ↗

Identification of a new complementation group of the peroxisome biogenesis disorders and PEX14 as the mutated gene.Semantic proximity Read ↗

[Human peroxisome-deficient disorders and pathogenic gene].Semantic proximity Read ↗

A Drosophila model for the Zellweger spectrum of peroxisome biogenesis disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.