Article
Isolation of a new peroxisome-deficient CHO cell mutant defective in peroxisome targeting signal-1 receptor.
Biochemical and biophysical research communications - 13 Jan 1997
Tsukamoto T, Bogaki A, Okumoto K, Tateishi K, Fujiki Y, Shimozawa N, Suzuki Y, Kondo N, Osumi T
Abstract excerpt
For the study of mechanism of peroxisome biogenesis, we attempted to isolate CHO cell mutants deficient in peroxisome biogenesis. We used as the parent strain a stable CHO transformant of rat PEX2 (formerly named peroxisome assembly factor-1) cDNA, to avoid unusually frequent isolation of Pex2 mutants. Among the three peroxisome-deficient mutants obtained, ZP102 was a new CHO mutant of complementation group 2,...
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