Article
Prevalence and clinical relevance of serum anti-p53 antibodies in patients with cholangiocarcinoma.
Asian Pacific journal of allergy and immunology - 1 Sept 2000
Tangkijvanich P, Kasemsupatana K, Janchai A, Kullavanijaya P, Theamboonlers A, Poovorawan Y
Abstract excerpt
Cholangiocarcinoma (CCA) constitutes carcinoma of the bile duct found at a high prevalence in northeastern Thailand. In the present study, we examined the sera of altogether 82 Thai CCA patients for the presence of anti-p53 antibodies in order to investigate a role of the tumor suppressor gene, p53 in the carcinogenesis. Our results revealed anti-p53 antibodies in 7.3% of the cases tested, which conforms to the...
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