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Article

CSF-1 deficiency in mice results in abnormal brain development.

Development (Cambridge, England) - 1 Sept 1996

Michaelson M D, Bieri P L, Mehler M F, Xu H, Arezzo J C, Pollard J W, Kessler J A

Abstract excerpt

Colony stimulating factor-1 (CSF-1) was initially identified as a growth factor for mononuclear phagocytes. This study examines the role of CSF-1 in the development of the central nervous system (CNS). CSF-1 treatment of neurons cultured from embryonic brain promoted survival and process outgrowth in a dose-dependent manner. By contrast, CSF-1 treatment of neurons cultured from the osteopetrotic (op/op) mouse, a...

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Identifiers

PMID: 8787741
DOI: 10.1242/dev.122.9.2661

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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