Article
Phenotypic differences between diabetes-prone BB rat sublines cosegregate with loci on chromosomes X and 10.
Biochemistry and molecular biology international - 1 Aug 1998
Klöting I, Kovacs P
Abstract excerpt
BB rat sublines, all developing an insulin-dependent diabetes, differ in several phenotypic traits and in the genotype. To study the genetic basis of phenotypic differences diabetic BB/OK and BB/Mol rats characterized by significantly different frequency and age at onset of diabetes were reciproc...
Topics
- Age of Onset
- Alleles
- Animals
- Chromosome Mapping
- Crosses, Genetic
- Diabetes Mellitus, Type 1
- Female
- Male
- Microsatellite Repeats
- Phenotype
- Rats
- Rats, Inbred BB
- Sex Characteristics
- X Chromosome