Genetic analysis of frequencies of phenotypes in the spontaneously diabetic BB rat--a main animal model of autoimmune type-I-diabetes.

Article

Genetic analysis of frequencies of phenotypes in the spontaneously diabetic BB rat--a main animal model of autoimmune type-I-diabetes.

Diabetes research (Edinburgh, Scotland) - 1 Jan 1993

Vogt L, Klöting I

Abstract excerpt

The incidence of diabetes shows variations of 40 to 80% in different BB rat sublines. Whether genetic or environmental factors are responsible for this observation remains unclear. Little data is available on population-based investigations and no results have been reported about computer-aided s...

Topics

Animals
Autoimmune Diseases
Crosses, Genetic
Diabetes Mellitus, Type 1
Female
Gene Frequency
Inbreeding
Incidence
Major Histocompatibility Complex
Male
Phenotype
Rats
Rats, Inbred BB

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