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Article

Influence of sex and phenotype of parents on the incidence of diabetes in BB/OK rat litters.

Diabete & metabolisme - 1 Jan 1993

Klöting I, Vogt L

Abstract excerpt

Because diabetes incidence (in the context of animal diabetes defined as percentage of animals developing diabetes until the age of 200 days) in BB rats is largely the same in males and females, a sex-influenced or sex-linked inheritance of diabetes has been excluded. However, in crossing studies using diabetic rats of the BB/OK rat subline and different diabetes-resistant rat strains, an excess of females was...

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PMID: 8314423

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Influence of sex and phenotype of parents on the incidence of diabetes in BB/OK rat litters.PMID 8314423Read ↗

Crosses between diabetic BB/OK and wild rats confirm that a third gene is essential for diabetes development.Semantic proximity Read ↗

Model-based prediction of diabetes incidence in BB/OK rats.Semantic proximity Read ↗

Genetic analysis of frequencies of phenotypes in the spontaneously diabetic BB rat--a main animal model of autoimmune type-I-diabetes.Semantic proximity Read ↗

Phenotypic differences between diabetes-prone BB rat sublines cosegregate with loci on chromosomes X and 10.Semantic proximity Read ↗

Contribution of animal models to the research of the causes of diabetesSemantic proximity Read ↗

Transplantation of adipose tissue protects BB/OK rats from type 1 diabetes development.Semantic proximity Read ↗

Mapping of novel genes predisposing or protecting diabetes development in the BB/OK rat.Semantic proximity Read ↗

Alleles of diabetes-resistant BN rats contribute to insulin-dependent type 1 diabetes mellitus.Semantic proximity Read ↗

High juvenile body weight and low insulin levels as markers preceding early diabetes in the BB rat.Semantic proximity Read ↗

Quantitative trait loci for blood glucose confirm diabetes predisposing and protective genes, Iddm4 and Iddm5r, in the spontaneously diabetic BB/OK rat.Semantic proximity Read ↗

Diabetes segregates as a single locus in crosses between inbred BB rats prone or resistant to diabetes.Semantic proximity Read ↗

Genetic variation in the multifunctional transcription factor Yy1 and type 1 diabetes mellitus in the BB rat.Semantic proximity Read ↗

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