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Article

Genetic association between cytochrome P450IA1 gene and susceptibility to Parkinson's disease.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 1996

Takakubo F, Yamamoto M, Ogawa N, Yamashita Y, Mizuno Y, Kondo I

Abstract excerpt

Idiopathic Parkinson's disease (PD) is a multifactorial neuro-degenerative disorder resulting from environmental factors acting on genetically susceptible individuals with normal aging. Cytochrome P450IA1 is a dioxin-inducible enzyme which is responsible for the activation of procarcinogens and environmental pollutants, such as benzo[alpha]pyrene and other aromatic hydrocarbons. The frequencies of polymorphic...

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PMID: 8872868
DOI: 10.1007/BF01273362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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