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Article

Assessment of hepatitis C virus sequence complexity by electrophoretic mobilities of both single-and double-stranded DNAs.

Journal of clinical microbiology - 1 Oct 1998

Wang Y M, Ray S C, Laeyendecker O, Ticehurst J R, Thomas D L

Abstract excerpt

To assess genetic variation in hepatitis C virus (HCV) sequences accurately, we optimized a method for identifying distinct viral clones without determining the nucleotide sequence of each clone. Twelve serum samples were obtained from seven individuals soon after they acquired HCV during a prospective study, and a 452-bp fragment from the E2 region was amplified by reverse transcriptase PCR and cloned....

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Share to Cloning, Molecular
Share to DNA, Viral
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Molecular Sequence Data

Share to Polymerase Chain Reaction

Share to Polymorphism, Single-Stranded Conformational

Share to Sensitivity and Specificity

Source

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Identifiers

PMID: 9738054
DOI: 10.1128/JCM.36.10.2982-2989.1998
PMCID: PMC105098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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