Assessment of hepatitis C virus sequence complexity by electrophoretic mobilities of both single-and double-stranded DNAs.

doi:10.1128/JCM.36.10.2982-2989.1998

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Assessment of hepatitis C virus sequence complexity by electrophoretic mobilities of both single-and double-stranded DNAs.

Journal of clinical microbiology - 1 Oct 1998

Wang Y M, Ray S C, Laeyendecker O, Ticehurst J R, Thomas D L

Abstract excerpt

To assess genetic variation in hepatitis C virus (HCV) sequences accurately, we optimized a method for identifying distinct viral clones without determining the nucleotide sequence of each clone. Twelve serum samples were obtained from seven individuals soon after they acquired HCV during a prosp...

Topics

Cloning, Molecular
DNA, Single-Stranded
DNA, Viral
Entropy
Genetic Variation
Hepacivirus
Hepatitis C
Humans
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Prospective Studies
Reverse Transcriptase Polymerase Chain Reaction
Sensitivity and Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 9738054
DOI: 10.1128/JCM.36.10.2982-2989.1998
PMCID: PMC105098

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9738054-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics