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Article

Accurate representation of the hepatitis C virus quasispecies in 5.2-kilobase amplicons.

Journal of clinical microbiology - 1 Sept 2004

Liu Zhi, Netski Dale M, Mao Qing, Laeyendecker Oliver, Ticehurst John R, Wang Xiao-Hong, Thomas David L, Ray Stuart C

Abstract excerpt

Hepatitis C virus (HCV) exists as a swarm of genetically distinct but related variants, or a quasispecies, whose complexity and sequence evolution are critical to studies of viral pathogenesis. Because most studies of the HCV quasispecies have focused on a relatively small genomic segment, the first hypervariable region of the E2 gene, it is possible that viral complexity is occasionally underestimated (due to...

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Identifiers

PMID: 15365015
DOI: 10.1128/JCM.42.9.4223-4229.2004
PMCID: PMC516368

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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