Article
Genotyping HIV-1 and HCV strains by a combinatorial DNA melting assay (COMA).
Molecular medicine (Cambridge, Mass.) - 1 Jul 1998
Kostrikis L G, Shin S, Ho D D
Abstract excerpt
BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) strains can be genetically classified into genetic lineages known as genetic types or subtypes according to phylogenetic analyses of complete or partial nucleotide sequences of their genomes. The genetic classific...
Topics
- Base Composition
- Biotinylation
- DNA, Viral
- Genotype
- HIV-1
- Hepacivirus
- Humans
- Kinetics
- Nucleic Acid Denaturation
- Nucleic Acid Heteroduplexes
- Nucleic Acid Hybridization
- Phylogeny
- Polymerase Chain Reaction
- Sensitivity and Specificity
- Temperature