Mouse models of genetic disease: new approaches, new paradigms.

Abstract excerpt

The mouse mutant resource is a valuable tool for gene function studies in the post-genomics era. However, despite a seemingly large catalogue of mouse mutants, it is recognized that we have access to mutations at only a small fraction of the total number of mouse genes. There is a phenotype gap t...

Topics

• Animals
• Disease Models, Animal
• Ethylnitrosourea
• Genetic Diseases, Inborn
• Humans
• Mice
• Mice, Mutant Strains
• Mutagenesis
• Mutagens
• Phenotype