Article
The K box, a conserved 3' UTR sequence motif, negatively regulates accumulation of enhancer of split complex transcripts.
Development (Cambridge, England) - 1 Oct 1998
Lai E C, Burks C, Posakony J W
Abstract excerpt
Cell-cell interactions mediated by the Notch receptor play an essential role in the development of the Drosophila adult peripheral nervous system (PNS). Transcriptional activation of multiple genes of the Enhancer of split Complex [E(spl)-C] is a key intracellular response to Notch receptor activity. Here we report that most E(spl)-C genes contain a novel sequence motif, the K box (TGTGAT), in their 3'...
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