Article
The K box, a conserved 3' UTR sequence motif, negatively regulates accumulation of enhancer of split complex transcripts.
Development (Cambridge, England) - 1 Oct 1998
Lai E C, Burks C, Posakony J W
Abstract excerpt
Cell-cell interactions mediated by the Notch receptor play an essential role in the development of the Drosophila adult peripheral nervous system (PNS). Transcriptional activation of multiple genes of the Enhancer of split Complex [E(spl)-C] is a key intracellular response to Notch receptor activ...
Topics
- 3' Untranslated Regions
- Animals
- Base Sequence
- Basic Helix-Loop-Helix Transcription Factors
- Consensus Sequence
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Evolution, Molecular
- Gene Expression Regulation, Developmental
- Genes, Insect
- Insect Proteins
- Larva
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Peripheral Nervous System
- Phenotype