Article
Full-length L1 elements have arisen recently in the same 1-kb region of the gorilla and human genomes.
Journal of molecular evolution - 1 Sept 1998
DeBerardinis R J, Kazazian H H
Abstract excerpt
New copies of the mammalian retrotransposon L1 arise in the germline at an undetermined rate. Each new L1 copy appears at a specific evolutionary time point that can be estimated by phylogenetic analysis. In humans, the active L1 sequence L1.2 resides at the genomic locus LRE1. Here we analyzed the region surrounding the LRE1 locus in humans and gorillas to determine the evolutionary history of the region and to...
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