Article
Tracing the LINEs of human evolution.
Proceedings of the National Academy of Sciences of the United States of America - 6 Aug 2002
Ovchinnikov Igor, Rubin Adrienne, Swergold Gary D
Abstract excerpt
The amplification of DNA by LINE-1 (L1) retrotransposons has created a large fraction of the human genome. To better understand their role in human evolution we endeavored to delineate the L1 elements that have amplified since the emergence of the hominid lineage. We used an approach based on shared sequence variants to trace backwards from the currently amplifying Ta subfamily. The newly identified groups of...
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