Article
Detection of mutations and polymorphism of N-acetyltransferase 1 gene in Indian, Malay and Chinese populations.
Pharmacogenetics - 1 Aug 1998
Zhao B, Lee E J, Yeoh P N, Gong N H
Abstract excerpt
The xenobiotic metabolizing enzymes N-acetyltransferases (NATs) are important for the biotransformation and/or bioactivation of drugs and carcinogens. NATs are coded for in humans by two distinct genes, designated NAT1 and NAT2. NAT1, which was originally thought to be monomorphic, was recently reported to exhibit variation in human populations. Recent studies suggested that a genetic polymorphism of NAT1 may be...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
