Article
Frequency of mutant CYP1A1, NAT2 and GSTM1 alleles in normal Indians and Malays.
Pharmacogenetics - 1 Oct 1995
Zhao B, Lee E J, Wong J Y, Yeoh P N, Gong N H
Abstract excerpt
Several xenobiotic metabolizing enzymes, including CYP1A1, NAT2 and GSTM1, are subject to genetic polymorphisms. Because these enzymes are important for the detoxification and/or bioactivation of drugs and carcinogens, these polymorphisms have important implications in therapeutics and cancer susceptibility. The distributions of CYP1A1, NAT2 and GSTM1 genotype frequencies in unrelated individuals of the Indian (n...
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