Article
Frequency of mutant CYP1A1, NAT2 and GSTM1 alleles in normal Indians and Malays.
Pharmacogenetics - 1 Oct 1995
Zhao B, Lee E J, Wong J Y, Yeoh P N, Gong N H
Abstract excerpt
Several xenobiotic metabolizing enzymes, including CYP1A1, NAT2 and GSTM1, are subject to genetic polymorphisms. Because these enzymes are important for the detoxification and/or bioactivation of drugs and carcinogens, these polymorphisms have important implications in therapeutics and cancer sus...
Topics
- Alleles
- Arylamine N-Acetyltransferase
- Asian People
- China
- Cytochrome P-450 Enzyme System
- Gene Frequency
- Genotype
- Glutathione Transferase
- Humans
- India
- Isoenzymes
- Malaysia
- Mutation
- Reference Values
- Xenobiotics