Article
A pilot study testing the association between N-acetyltransferases 1 and 2 and risk of oral squamous cell carcinoma in Japanese people.
Carcinogenesis - 1 Oct 1998
Katoh T, Kaneko S, Boissy R, Watson M, Ikemura K, Bell D A
Abstract excerpt
Risk of oral cancer has been associated with exposure to tobacco smoke, alcohol and with genetic predisposition. The aromatic amines and their metabolites, a class of carcinogens present in tobacco smoke, undergo metabolism (activation or detoxification) through an N- or O-acetylation pathway by...
Topics
- Acetylation
- Aged
- Alleles
- Arylamine N-Acetyltransferase
- Base Sequence
- Carcinoma, Squamous Cell
- DNA Primers
- Female
- Gene Frequency
- Genotype
- Humans
- Isoenzymes
- Japan
- Male
- Middle Aged
- Mouth Neoplasms
- Pilot Projects
- Polymorphism, Genetic