Human leukocyte antigen-C genes and susceptibility to primary sclerosing cholangitis.

doi:10.1002/hep.510280309

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Article

Human leukocyte antigen-C genes and susceptibility to primary sclerosing cholangitis.

Hepatology (Baltimore, Md.) - 1 Sept 1998

Moloney M M, Thomson L J, Strettell M J, Williams R, Donaldson P T

Abstract excerpt

Genetic susceptibility to primary sclerosing cholangitis (PSC) is associated with the extended HLA A1-B8-DR3 haplotype and also with the DRB3*0101-DRB1*0301-DQA1*0103-DQB1*0603 haplotype. However, very few studies have considered the role of HLA C which lies between HLA A and B, is highly polymor...

Topics

Alleles
Cholangitis, Sclerosing
Disease Susceptibility
Female
HLA-C Antigens
HLA-DR Antigens
Haplotypes
Humans
Male
Middle Aged
T-Lymphocytes

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