Article
HLA-C genes and susceptibility to type 1 autoimmune hepatitis.
Hepatology (Baltimore, Md.) - 1 Oct 1997
Strettell M D, Thomson L J, Donaldson P T, Bunce M, O'Neill C M, Williams R
Abstract excerpt
Susceptibility to autoimmune hepatitis (AIH) is associated with the HLA A1-B8-DR3 haplotype, DR4 antigen, and, more specifically, the HLA DRB3*0101, DRB1*0301, and DRB1*0401 alleles. Few investigators, however, have examined the HLA C locus in AIH, which warrants detailed study in view of its recently described roles in immunoregulation. Eighty-seven adult, white patients with well-characterized type 1 AIH and...
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