HLA-C genes and susceptibility to type 1 autoimmune hepatitis.

doi:10.1002/hep.510260434

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Article

HLA-C genes and susceptibility to type 1 autoimmune hepatitis.

Hepatology (Baltimore, Md.) - 1 Oct 1997

Strettell M D, Thomson L J, Donaldson P T, Bunce M, O'Neill C M, Williams R

Abstract excerpt

Susceptibility to autoimmune hepatitis (AIH) is associated with the HLA A1-B8-DR3 haplotype, DR4 antigen, and, more specifically, the HLA DRB3*0101, DRB1*0301, and DRB1*0401 alleles. Few investigators, however, have examined the HLA C locus in AIH, which warrants detailed study in view of its rec...

Topics

Adult
Alleles
Autoimmune Diseases
Disease Susceptibility
Female
Genotype
HLA-C Antigens
HLA-DR Antigens
Hepatitis
Humans
Linkage Disequilibrium
Male

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