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Article

The coding region of the Bloom syndrome BLM gene and of the CBL proto-oncogene is mutated in genetically unstable sporadic gastrointestinal tumors.

Cancer research - 1 Sept 1998

Calin G, Herlea V, Barbanti-Brodano G, Negrini M

Abstract excerpt

Microsatellite instability (MSI) characterizes the hereditary nonpolyposis colorectal cancer syndrome but is also found in sporadic tumors. Frameshifts in microsatellites found in the coding regions (CDRs) of the TGFbeta1-RII, IGFIIR, hMSH3, hMSH6, and BAX genes indicate that MSI is involved in t...

Topics

Adenosine Triphosphatases
Bloom Syndrome
DNA Helicases
Gastrointestinal Neoplasms
Humans
Microsatellite Repeats
Mutation
Proto-Oncogene Mas
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-cbl
Proto-Oncogenes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RecQ Helicases

Ubiquitin-Protein Ligases

Source

Identifiers

PMID: 9731483

Genes

BLM
CBL
HOXA1
BAX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9731483-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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The coding region of the Bloom syndrome BLM gene and of the CBL proto-oncogene is mutated in genetically unstable sporadic gastrointestinal tumors.PMID 9731483Read ↗

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