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Article

Functional activity of epidermal growth factor receptors in autosomal recessive polycystic kidney disease

1 Sept 1998

Abstract excerpt

Evidence from a number of laboratories suggests a potential role for the epidermal growth factor (EGF)-transforming growth factor-alpha-epidermal growth factor receptor (EGF-R) axis in promoting epithelial hyperplasia and cyst formation in autosomal recessive polycystic kidney disease (ARPKD). As previously reported, in the C57BL-6Jcpk/cpk (CPK), BALB/c-bpk/bpk (BPK), and C3H-orpk/orpk (ORPK) murine models of...

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Identifiers

PMID: 9729511
DOI: 10.1152/ajprenal.1998.275.3.f387

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Functional activity of epidermal growth factor receptors in autosomal recessive polycystic kidney diseasePMID 9729511Read ↗

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