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Article

Development of autosomal recessive polycystic kidney disease in BALB/c-cpk/cpk mice.

Journal of the American Society of Nephrology : JASN - 1 Oct 2000

Ricker Justin L, Gattone Vincent H, Calvet James P, Rankin Carolyn A

Abstract excerpt

Autosomal recessive polycystic kidney disease (ARPKD) is a rare but devastating inherited disease in humans. Various strains of mice that are homozygous for the cpk gene display renal pathology similar to that seen in human ARPKD. The PKD progresses to renal insufficiency, azotemia, and ultimately a uremic death by approximately 3 wk of age. This study characterizes PKD in mice that are homozygous for the cpk...

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Source

Identifiers

PMID: 11004214
DOI: 10.1681/ASN.V11101837

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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